Purity of aspirin by spectrophotometry

Chemistry of aspirin

Using a series of different aspirin concentrations a spectrophotometer can measure each solution and a calibration curve can be constructed as a baseline for the amount of aspirin in a given aspirin product. The medicinal pain killing values of acetylsalicylic were already known at the time, but so was its most common side effect which was stomach upset. Words: , Paragraphs: 8, Pages: 3 Publication date: January 05, Sorry, but copying text is forbidden on this website! This use of spectrophotometers allows manufacturers to keep their products consistent across the board. The mass of acetylsalicylic acid was determined using a analytical balance. When this green is removed from normal white light, we observe violet therefore, green is the compliment of violet. If green light is directed into a solution that contains this aspirin complex, some of the green light will be absorbed. Gerhardt did not pursue marketing his buffered product and thus it remained fairly unknown for years. The technological leader in color and light measurement solutions, Konica Minolta Sensing Americas helps organizations formulate, evaluate, and control color to meet product quality and operational goals more efficiently. Aspirin whose chemical name is acetylsalicylic acid was derived from a compound called salicylic acid. Salicylic acid produces a salicylate dianion, when dissolved in water, which reacts with an acidic solution Fe NO3 3 aq , to produce a strong violet tetraaquosalicylatroiron III complex. The intensity of the green light leaving the sample, I, is less than the original intensity of the green light, I0.

This use of spectrophotometers allows manufacturers to keep their products consistent across the board. This absorption of green light can be used to quantitatively determine the amount of aspirin present in the solution.

Using a series of different aspirin concentrations a spectrophotometer can measure each solution and a calibration curve can be constructed as a baseline for the amount of aspirin in a given aspirin product.

Spectrophotometric analysis of aspirin answers

The violet color of the complex results from the fact that the complex strongly absorbs green light. Hoffman, who worked for Bayer, informed the company of the results and the rest as they say is history. We can talk about the fraction of light that was transmitted through the sample, transmittance T ; or we can talk about the amount of light that was absorbed by the sample, absorbance A. This use of spectrophotometers allows manufacturers to keep their products consistent across the board. To put it simply there is a visible violet color reaction. Words: , Paragraphs: 8, Pages: 3 Publication date: January 05, Sorry, but copying text is forbidden on this website! Get Essay The percentage purity of aspirin was found to be Because today's aspirin is mass produced in tablet form, Spectrophotometers are a reliable and economical way to keep the purity of Aspirin consistent throughout the manufacturing process. The medicinal pain killing values of acetylsalicylic were already known at the time, but so was its most common side effect which was stomach upset. The intensity of the color is related to the purity and concentration of aspirin in a tablet. Salicylic acid may be irritating because it is an acid; therefore one of the acidic parts was covered up with an acetyl group, converting it to acetylsalicylic acid ASA.

Get Essay The percentage purity of aspirin was found to be The mass of acetylsalicylic acid was determined using a analytical balance. Here's why: when iron is added to aspirin, it produces violet tetraaquosalicylatroiron complex. ASA not only could reduce fever and relieve pain and swelling, but better for the stomach and worked even better than salicylic acid.

How to determine the purity of aspirin

So, if we know the concentration of the complex, we know the concentration of the aspirin. Sodium hydroxide NaOH was added to the acetylsalicylic acid and heated in order to hydrolyze acetylsalicylic acid. This absorption of green light can be used to quantitatively determine the amount of aspirin present in the solution. Transmittance is inversely proportional to absorbance: the more light that passes through the sample, the higher the transmittance and the lower the absorbance; conversely, the less light that passes through the sample, the lower the transmittance and the higher the absorbance. Gerhardt did not pursue marketing his buffered product and thus it remained fairly unknown for years. Introduction Aspirin is a member of a family of chemicals called salicylates. Phenols such as salicylic acid react with iron chloride to form coloured violet complexes Aspirin easily absorbs green light and green is the compliment of violet, which allows a determination of the amount of aspirin present. We can talk about the fraction of light that was transmitted through the sample, transmittance T ; or we can talk about the amount of light that was absorbed by the sample, absorbance A.

Words:Paragraphs: 8, Pages: 3 Publication date: January 05, Sorry, but copying text is forbidden on this website! The intensity of the green light leaving the sample, I, is less than the original intensity of the green light, I0. Gerhardt did not pursue marketing his buffered product and thus it remained fairly unknown for years.

what affects purity of aspirin

The absorbance of a solution is directly proportional to the concentration of that solution.

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How Spectrophotometers Can Ensure the Purity of Aspirin